Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.67 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
| ▸ | IL1B | P01584 | 1/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.57 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24319836 | 0.95 | CRBN (0.67) | CRBNIKZF1BRD4TNFIL1B | |
| SCHEMBL24319681 | 0.95 | CRBN (0.67) | CRBNIKZF1BRD4TNFIL1B | |
| SCHEMBL23509388 | 0.95 | CRBN (0.67) | CRBNIKZF1BRD4TNFIL1B | |
| SCHEMBL22557008 | 0.90 | CRBN (0.69) | CRBNIKZF1BRD4TNFIL1B | |
| SCHEMBL29876913 | 0.90 | CRBN (0.69) | CRBNIKZF1BRD4TNFIL1B | |
| SCHEMBL23128979 | 0.86 | CRBN (0.65) | CRBNIKZF1IKZF2 | |
| SCHEMBL24779145 | 0.85 | CRBN (0.63) | CRBNIKZF1BRD4TNFIL1B | |
| SCHEMBL24921704 | 0.85 | CRBN (0.67) | CRBNIKZF1IKZF2CSNK1A1 | |
| SCHEMBL25012213 | 0.85 | CRBN (0.63) | CRBNIKZF1DDB1IKZF2CSNK1A1 | |
| SCHEMBL24294480 | 0.85 | CRBN (0.67) | CRBNIKZF1IKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |