SCHEMBL22705751

SCHEMBL22705751

c1ccc(-c2nc3ccccc3n2-c2cccc3c(-c4cccc5ccccc45)c4cccc(-n5c(-c6ccccc6)nc6ccccc65)c4cc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
GSR P00390 2/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
POLB P06746 1/20 0.42
KMT2A Q03164 5/20 0.40
MEN1 O00255 3/20 0.40
FLT3 P36888 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 2/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
PTGS2 P35354 2/20 0.39
NPC1 O15118 1/20 0.39
NTRK1 P04629 1/20 0.39
ALOX5 P09917 1/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22705784 0.94 GSR (0.43) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22707355 0.94 ESR1 (0.45) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL26343956 0.93 ESR1 (0.46) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22706844 0.92 GSR (0.40) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22706584 0.92 ESR1 (0.40) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22708121 0.91 ESR1 (0.45) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22706117 0.90 ESR1 (0.41) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22706448 0.90 ESR1 (0.41) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22707373 0.89 ESR1 (0.43) ESR1ESR2GSRALDH1A1KDM4E
SCHEMBL22706429 0.89 ESR1 (0.45) ESR1ESR2GSRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed