Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22706913 | 0.90 | TSHR (0.43) | TSHRMAPK1HTTHSD11B1GSR | |
| SCHEMBL22705722 | 0.88 | ESR1 (0.36) | TSHRHTTGSRALDH1A1LMNA | |
| SCHEMBL22707689 | 0.86 | TSHR (0.47) | TSHRMAPK1HTTGSRPIK3CD | |
| SCHEMBL22705665 | 0.85 | TSHR (0.46) | TSHRMAPK1HTTGSRPIK3CD | |
| SCHEMBL22706472 | 0.83 | TSHR (0.43) | TSHRMAPK1HTTGSRPIK3CD | |
| SCHEMBL22705813 | 0.81 | TSHR (0.46) | TSHRMAPK1HTTGSRPIK3CD | |
| SCHEMBL22707736 | 0.81 | TSHR (0.42) | TSHRMAPK1HTTHSD11B1GSR | |
| SCHEMBL22705749 | 0.79 | TSHR (0.54) | TSHRMAPK1HTTGSRPIK3CD | |
| SCHEMBL22707631 | 0.79 | TSHR (0.46) | TSHRMAPK1HTTGSRPIK3CD | |
| SCHEMBL22705701 | 0.79 | TSHR (0.42) | TSHRMAPK1HTTGSRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200373496-A1 | ORGANIC LIGHT EMITTING ELEMENT | LG CHEM, LTD. (KR) | 2020-11-26 | — | — | US | disclosed |