SCHEMBL2270976

SCHEMBL2270976

Nc1cccc(-c2nc3cc(N)ccc3o2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 15/20 0.78
RAB9A P51151 14/20 0.78
MAPT P10636 11/20 0.78
SMN1; SMN2 Q16637 10/20 0.78
KDM4E B2RXH2 9/20 0.78
TP53 P04637 8/20 0.78
ALDH1A1 P00352 6/20 0.78
KMT2A Q03164 5/20 0.78
HSD17B10 Q99714 5/20 0.78
MEN1 O00255 4/20 0.78
NFKB1 P19838 2/20 0.78
NFKB2 Q00653 2/20 0.78
RELA Q04206 2/20 0.78
GFER P55789 3/20 0.73
RXFP1 Q9HBX9 2/20 0.73
HPGD P15428 3/20 0.72
GAA P10253 1/20 0.72
CACNA1B Q00975 1/20 0.72
APBA1 Q02410 1/20 0.72
PIK3CB P42338 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364223 1.00 NPC1 (0.78) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL16424109 0.95 NPC1 (0.80) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL29838123 0.95 NPC1 (0.80) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL12209706 0.90 NPC1 (0.72) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL12209714 0.88 NPC1 (0.70) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL2244861 0.88 NPC1 (0.81) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL30621734 0.88 NPC1 (0.81) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL2245287 0.88 RAB9A (0.79) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL6681353 0.88 NPC1 (0.70) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL2250992 0.88 SMN1; SMN2 (0.70) NPC1RAB9AMAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431780-A High-strength high-modulus high-toughness shape memory poly (benzimidazole-benzoxazole) imide material with controllable photodegradation and preparation method thereof 哈尔滨工业大学 2025-02-14 CN claimed
CN-119307175-A Hydrophobic aramid fiber coating liquid for lithium ion battery, coating diaphragm and preparation method 烟台泰和电池新材料科技有限公司 2025-01-14 CN claimed
CN-116200881-B Heterocyclic aramid nanofiber membrane and preparation method thereof 四川大学 2024-12-24 CN claimed
US-12060457-B2 Resin composition for display substrate, resin film for display substrate and laminate body containing this, image display device, organic EL display, and manufacturing method of these TORAY INDUSTRIES, INC. (JP) 2024-08-13 US claimed
CN-115819760-B High-temperature-resistant polyamide acid slurry and preparation method and application thereof 上海市塑料研究所有限公司 2024-07-23 CN claimed
CN-114685787-B Polyimide film with synergistic crosslinking structure and preparation method and application thereof 上海市塑料研究所有限公司 2024-03-08 CN claimed
CN-112384546-B Thermally conductive resin composition 东洋纺株式会社 2024-01-16 CN claimed
CN-112980014-B Blended polyimide film, preparation method thereof and application thereof in flexible display substrate 上海市合成树脂研究所有限公司 2023-08-08 CN claimed
CN-116200881-A Heterocyclic aramid nanofiber membrane and preparation method thereof 四川大学 2023-06-02 CN claimed
CN-115894988-A Polyimide-polyamide imide film and preparation method thereof 上海市塑料研究所有限公司 2023-04-04 CN claimed
CN-109721749-A A kind of thermostable type Kapton and preparation method containing heteroaromatic 上海市合成树脂研究所有限公司 2019-05-07 CN claimed
US-9394638-B2 Polyimide nonwoven fabric and process for production thereof TOYO BOSEKI KABUSHIKI KAISHA (JP) 2016-07-19 US claimed
EP-0789723-B1 POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS MICHIGAN MOLECULAR INST (US) 2001-12-05 EP claimed
US-5985969-A REACTION PRODUCT OF PYROMELLITIC DIANHYDRIDE AND DIAMINO BENZOXAZOLE WITH CHAIN EXTENDERS FOR COATING ON SUBSTRATES THE DOW CHEMICAL COMPANY (US) 1999-11-16 US claimed
US-5919892-A CYCLIZED TO POLYIMIDEBENZOXAZOLE THE DOW CHEMICAL COMPANY (US) 1999-07-06 US claimed
US-5741585-A Polyamic acid precursors and methods for preparing higher molecular weight polyamic acids and polyimidebenzoxazole THE DOW CHEMICAL COMPANY (US) 1998-04-21 US claimed
EP-0822954-A1 POLYAMIC ACID PRECURSORS AND METHOD FOR PREPARING POLYIMIDEBENZOXAZOLE THE DOW CHEMICAL COMPANY (US) 1998-02-11 EP claimed
EP-0789723-A1 POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS THE DOW CHEMICAL COMPANY (US) 1997-08-20 EP claimed
WO-1996034033-A1 POLYAMIC ACID PRECURSORS AND METHOD FOR PREPARING POLYIMIDEBENZOXAZOLE THE DOW CHEMICAL COMPANY (US) 1996-10-31 WO claimed
WO-1996013541-A1 POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS THE DOW CHEMICAL COMPANY (US) 1996-05-09 WO claimed