Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 11/20 | 0.65 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27437137 | 0.92 | SCN5A (0.55) | SCN5ASCN1ASCN2ACYP1A2MAPK14 | |
| SCHEMBL23115999 | 0.90 | SCN5A (0.53) | SCN5ASCN1ASCN2ACYP1A2MAPK14 | |
| SCHEMBL23116256 | 0.88 | SCN5A (0.51) | SCN5ASCN1ASCN2ACYP1A2MAPK14 | |
| SCHEMBL23115997 | 0.88 | SCN5A (0.50) | SCN5ASCN1ASCN2ACYP1A2MAPK14 | |
| SCHEMBL23116250 | 0.87 | SCN5A (0.48) | SCN5ASCN1ASCN2ACYP1A2DGAT1 | |
| SCHEMBL23116141 | 0.86 | SCN5A (0.48) | SCN5ASCN1ASCN2ACYP1A2MAPK14 | |
| SCHEMBL22712654 | 0.85 | SCN5A (0.52) | SCN5ACYP1A2MAPK14DGAT1 | |
| SCHEMBL31308491 | 0.85 | SCN5A (0.47) | SCN5ASCN1ASCN2ACYP1A2MAPK14 | |
| SCHEMBL23116019 | 0.85 | SCN5A (0.47) | SCN5ASCN1ASCN2ACYP1A2MAPK14 | |
| SCHEMBL20204062 | 0.84 | CYP1A2 (0.66) | SCN5ASCN1ASCN2ACYP1A2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129066-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2025-04-24 | — | — | US | disclosed |
| US-12030881-B2 | Ion channel modulators | PRAXIS PRECISION MEDICINES, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030881-B2 | Ion channel modulators | PRAXIS PRECISION MEDICINES, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030881-B2 | Ion channel modulators | PRAXIS PRECISION MEDICINES, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20220204505-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2022-06-30 | — | — | US | disclosed |
| US-20220204505-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2022-06-30 | — | — | US | disclosed |
| US-11279700-B2 | Ion channel modulators | PRAXIS PRECISION MEDICINES, INC. (US) | 2022-03-22 | — | — | US | disclosed |
| US-11279700-B2 | Ion channel modulators | PRAXIS PRECISION MEDICINES, INC. (US) | 2022-03-22 | — | — | US | disclosed |
| US-20200377499-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2020-12-03 | — | — | US | disclosed |
| US-20200377499-A1 | ION CHANNEL MODULATORS | PRAXIS PRECISION MEDICINES, INC. | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030881-B2 | Ion channel modulators | SCN1A, SCN1B, SCN2A | SCN5A 5/4885SCN1A 1/4885SCN2A 3/4885 |
| US-11279700-B2 | Ion channel modulators | SCN1A, SCN1B, SCN2A | SCN5A 5/4885SCN1A 1/4885SCN2A 3/4885 |
| US-20220204505-A1 | ION CHANNEL MODULATORS | SCN1A, SCN1B, SCN2A | SCN5A 5/4885SCN1A 1/4885SCN2A 3/4885 |
| US-20250129066-A1 | ION CHANNEL MODULATORS | SCN1A, SCN1B, SCN2A | SCN5A 5/4885SCN1A 1/4885SCN2A 3/4885 |
| US-20200377499-A1 | ION CHANNEL MODULATORS | SCN1A, SCN1B, SCN2A | SCN5A 5/4885SCN1A 1/4885SCN2A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.