SCHEMBL22712971

SCHEMBL22712971

CC(C)(C)OC(=O)NCCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 17/20 0.67
MEN1 O00255 1/20 0.56
GAA P10253 1/20 0.56
KMT2A Q03164 1/20 0.56
RIMKLA Q8IXN7 1/20 0.54
NAALAD2 Q9Y3Q0 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20341475 1.00 FOLH1 (0.67) FOLH1MEN1GAAKMT2ARIMKLA
SCHEMBL18145839 1.00 FOLH1 (0.67) FOLH1MEN1GAAKMT2ARIMKLA
SCHEMBL31476179 0.87 FOLH1 (0.52) FOLH1MEN1GAAKMT2A
SCHEMBL3445777 0.86 MEN1 (0.65) FOLH1MEN1GAAKMT2A
SCHEMBL391537 0.86 MEN1 (0.65) FOLH1MEN1GAAKMT2A
SCHEMBL10241524 0.86 MEN1 (0.65) FOLH1MEN1GAAKMT2A
SCHEMBL13399503 0.86 FOLH1 (0.57) FOLH1MEN1GAAKMT2A
SCHEMBL30000512 0.85 MEN1 (0.51) FOLH1MEN1GAAKMT2A
SCHEMBL24580520 0.85 MEN1 (0.63) FOLH1MEN1GAAKMT2A
Hydrochloric Acid SCHEMBL28881885 0.85 MEN1 (0.63) FOLH1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885GAA 125/4885
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885GAA 125/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885GAA 125/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885GAA 125/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885GAA 125/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885MEN1 59/4885GAA 125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.