SCHEMBL22713857

SCHEMBL22713857

Cc1cc(=O)cc(C)n1C=Cc1ccc(OC(F)F)c(O)c1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PDE4B Q07343 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22713855 1.00 PDE4B (0.74) PDE4B
SCHEMBL30352597 1.00 PDE4B (0.74) PDE4B
SCHEMBL30352669 1.00 PDE4B (0.74) PDE4B
SCHEMBL22713940 0.85 PDE4B (1.00) PDE4B
SCHEMBL22713941 0.85 PDE4B (1.00) PDE4B
SCHEMBL30352704 0.84 PDE4B (0.67) PDE4B
SCHEMBL22713953 0.84 PDE4B (0.67) PDE4B
SCHEMBL22713948 0.84 PDE4B (0.67) PDE4B
SCHEMBL22713859 0.80 PDE4B (0.73) PDE4B
SCHEMBL22714011 0.80 PDE4B (0.73) PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3777979-B1 ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) 2024-01-17 — — EP disclosed
CN-110407741-B Anti-inflammatory compound and preparation and application thereof 启元生物(杭州)有限公司 2023-03-21 — — CN disclosed
US-11440886-B2 Anti-inflammatory compound, and preparation and use thereof E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd. (CN) 2022-09-13 — — US disclosed
EP-3777979-A1 ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF Vivavision Biotech, Inc. (CN) 2021-02-17 — — EP disclosed
US-20200377460-A1 ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF VIVAVISION BIOTECH, INC. (CN) 2020-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440886-B2 Anti-inflammatory compound, and preparation and use thereof PDE4B, PDE4A, PDE7A PDE4B 1/4885
US-20200377460-A1 ANTI-INFLAMMATORY COMPOUND, AND PREPARATION AND USE THEREOF PDE4B, PDE4A, PDE7A PDE4B 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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