Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Fumarate SCHEMBL2705043 | 0.87 | HCAR2 (0.62) | TSHRHPGDALDH1A1HCAR2MAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL2168299 | 0.87 | HCAR2 (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL34965 | 0.85 | — | — | |
| SCHEMBL321481 | 0.85 | TSHR (0.36) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14999268 | 0.84 | GAA (0.53) | TSHRALDH1A1TP53THRBSMN1; SMN2 | |
| Acrylic Acid Ethyl Ester SCHEMBL10892530 | 0.84 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| Potassium SCHEMBL31173511 | 0.83 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL3171614 | 0.83 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid Ethyl Ester SCHEMBL3180 | 0.83 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL9557413 | 0.83 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110197472-A1 | PROCESS FOR PRODUCING CROSSLINKED MOLDED FOAM AND CROSSLINKED MOLDED FOAM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-0016493-B1 | COPOLYMER ELASTOMER WITH IMPROVED HEAT AND OIL RESISTANCE BASED ON MODIFIED CHLORINATED POLYETHYLENE | UNIROYAL, INC. (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4238578-A | GRAFT POLYMER WITH ACRYLIC ESTER; VULCANIZABLE | UNIROYAL, INC. (US) | 1980-12-09 | — | — | US | disclosed |
| EP-0016493-A1 | Copolymer elastomer with improved heat and oil resistance based on modified chlorinated polyethylene | UNIROYAL, INC. (US) | 1980-10-01 | — | — | EP | disclosed |