SCHEMBL22717246

SCHEMBL22717246

COc1ccc(F)c(-c2ccc(OC(=O)c3cccc([C@@H](CC(=O)O)C4CC4)c3)c(C)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22717247 1.00 FFAR1 (0.65) FFAR1
SCHEMBL22717243 0.93 FFAR1 (0.55) FFAR1
SCHEMBL22717392 0.84 FFAR1 (0.75) FFAR1
SCHEMBL22717390 0.84 FFAR1 (0.75) FFAR1
SCHEMBL29454543 0.82 FFAR1 (0.60) FFAR1
SCHEMBL22717447 0.82 FFAR1 (0.60) FFAR1
SCHEMBL22717448 0.82 FFAR1 (0.60) FFAR1
SCHEMBL22717523 0.76 FFAR1 (0.64) FFAR1
SCHEMBL22717521 0.76 FFAR1 (0.64) FFAR1
SCHEMBL29454660 0.76 FFAR1 (0.64) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976576-A1 GPR40 AGONISTS Kallyope, Inc. (US) 2022-04-06 EP disclosed
WO-2020242943-A1 GPR40 AGONISTS KALLYOPE, INC. (US) 2020-12-03 WO disclosed