Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | F12 | P00748 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029606 | 0.84 | ADORA1 (0.38) | ADORA1F12PDE10AC5AR1DDB1 | |
| SCHEMBL22029563 | 0.80 | PDE10A (0.39) | ADORA1F12PDE10AC5AR1DDB1 | |
| SCHEMBL22029691 | 0.79 | ADORA1 (0.51) | ADORA1F12C5AR1DDB1CRBN | |
| SCHEMBL22102760 | 0.78 | PARP1 (0.40) | ADORA1F12PDE10AC5AR1DDB1 | |
| SCHEMBL22069271 | 0.78 | ADORA1 (0.39) | ADORA1F12PDE10AC5AR1MAPT | |
| SCHEMBL22069457 | 0.77 | ADORA1 (0.38) | ADORA1F12PDE10AC5AR1DDB1 | |
| SCHEMBL22716252 | 0.76 | ADORA1 (0.43) | ADORA1F12C5AR1DDB1CRBN | |
| SCHEMBL22068976 | 0.74 | PDE10A (0.36) | ADORA1F12PDE10AC5AR1DDB1 | |
| SCHEMBL22715571 | 0.74 | ADORA1 (0.46) | ADORA1F12PDE10AC5AR1DDB1 | |
| SCHEMBL22624658 | 0.73 | DDB1 (0.36) | ADORA1F12PDE10AC5AR1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976617-B1 | FUSED HETEROCYCLIC DERIVATIVES | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2025-04-23 | — | — | EP | disclosed |
| WO-2020243135-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-12-03 | — | — | WO | disclosed |