Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220045 | 0.91 | HPGD (0.50) | HRH3HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL12186260 | 0.91 | HPGD (0.50) | HRH3HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL223042 | 0.91 | HPGD (0.50) | HRH3HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL220850 | 0.91 | HPGD (0.50) | HRH3HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL221146 | 0.91 | HPGD (0.50) | HRH3HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL222625 | 0.91 | HPGD (0.50) | HRH3HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL12272010 | 0.91 | HPGD (0.50) | HRH3HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL2475421 | 0.88 | HPGD (0.52) | HRH3HPGDMAPTEPHX1USP2 | |
| SCHEMBL2475425 | 0.88 | HPGD (0.52) | HRH3HPGDMAPTEPHX1USP2 | |
| SCHEMBL2477634 | 0.87 | HPGD (0.52) | HRH3HPGDMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |