SCHEMBL22720333 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	HPGD	P15428	1/20	0.47

▸	MEN1	O00255	2/20	0.46

▸	KMT2A	Q03164	2/20	0.46

▸	ALDH1A1	P00352	1/20	0.46

▸	MAPT	P10636	1/20	0.46

▸	PREP	P48147	2/20	0.43

▸	FPR2	P25090	1/20	0.43

▸	EPHX1	P07099	1/20	0.42

▸	HRH3	Q9Y5N1	4/20	0.41

▸	USP2	O75604	1/20	0.40

▸	SMN1; SMN2	Q16637	1/20	0.40

▸	GPR119	Q8TDV5	1/20	0.39

▸	RECQL	P46063	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2797599	0.90	HPGD (0.44)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL2799529	0.90	HPGD (0.44)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL2797597	0.90	HPGD (0.44)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL222625	0.89	HPGD (0.50)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL12272010	0.89	HPGD (0.50)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL12186260	0.89	HPGD (0.50)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL221146	0.89	HPGD (0.50)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL220850	0.89	HPGD (0.50)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL220045	0.89	HPGD (0.50)	HPGDMEN1KMT2AALDH1A1MAPT
SCHEMBL223042	0.89	HPGD (0.50)	HPGDMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020239123-A1	AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF	上海翰森生物医药科技有限公司	2020-12-03	—	—	WO	disclosed