Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15139606 | 1.00 | NR1H2 (0.57) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL15171534 | 1.00 | NR1H2 (0.57) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL3118155 | 0.92 | NR1H2 (0.56) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL29105803 | 0.89 | NR1H2 (0.51) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL29105861 | 0.89 | NR1H2 (0.51) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL19837164 | 0.89 | NR1H2 (0.51) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL18383163 | 0.89 | NR1H2 (0.51) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL19837042 | 0.89 | NR1H2 (0.51) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL2917795 | 0.89 | NR1H2 (0.51) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL2917798 | 0.89 | NR1H2 (0.51) | NR1H2USP2SMN1; SMN2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239077-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |