Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL17956832 | 0.86 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27588067 | 0.85 | TDP1 (0.52) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28092409 | 0.84 | TDP1 (0.56) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27653299 | 0.83 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL17956858 | 0.81 | TDP1 (0.52) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27893274 | 0.79 | TDP1 (0.62) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28331255 | 0.78 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL17956883 | 0.78 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27473155 | 0.78 | TDP1 (0.68) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28092916 | 0.78 | TDP1 (0.68) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016518-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2023-02-16 | — | — | WO | disclosed |
| WO-2020239103-A1 | BTK INHIBITOR RING DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2020-12-03 | — | — | WO | disclosed |
| CN-107207464-B | Substituted dihydro-isoquinoline ketone compound | 辉瑞大药厂 | 2019-10-22 | — | — | CN | disclosed |
| CN-104955826-B | It can be used for treating spiral shell-Quinzolone derivatives of neurological disorder and illness | 默克专利股份公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-105829285-A | Quinazolinone and isoquinolinone derivatives | 中外制药株式会社 | 2016-08-03 | — | — | CN | disclosed |
| CN-103517907-B | Volution isoxazolines derivative as antiparasitic | 硕腾服务有限责任公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-104955826-A | SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS | MERCK PATENT GMBH | 2015-09-30 | — | — | CN | disclosed |
| CN-104812758-A | Crystalline forms of 1- (5' - (5- (3, 5-dichloro-4-fluorophenyl) -5- (trifluoromethyl) -4, 5-dihydroisoxazol-3-yl) -3' H-spiro [ azetidine-3, 1' -isobenzofuran ] -1-yl) -2- (methylsulfonyl) ethanone | ZOETIS LLC | 2015-07-29 | — | — | CN | disclosed |
| CN-104603139-A | Spirocyclic derivatives as antiparasitic agents | ZOETIS LLC | 2015-05-06 | — | — | CN | disclosed |
| CN-104387372-A | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV | 2015-03-04 | — | — | CN | disclosed |
| CN-104114557-A | 8-substituted 2-amino- [1,2,4] triazolo [1,5-a ] pyrazines as SYK tyrosine kinase inhibitors and GCN2 serine kinase inhibitors | MERCK PATENT GMBH | 2014-10-22 | — | — | CN | disclosed |
| CN-103788098-A | Azetidine and cyclobutane derivatives as JAK inhibitors | INCYTE CORP | 2014-05-14 | — | — | CN | disclosed |
| CN-102026999-B | Azetidine and cyclobutane derivatives as JAK inhibitors | INCYTE CORP | 2014-03-05 | — | — | CN | disclosed |
| CN-103517907-A | Spirocyclic isoxazoline derivatives as antiparasitic agents | PFIZER | 2014-01-15 | — | — | CN | disclosed |
| CN-102026999-A | Azetidine and cyclobutane derivatives as JAK inhibitors | INCYTE CORP | 2011-04-20 | — | — | CN | disclosed |