Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436735 | 1.00 | POLB (0.52) | POLBL3MBTL1TSHRMAPK1CYP2D6 | |
| SCHEMBL12513455 | 0.94 | POLB (0.57) | POLBL3MBTL1TSHRMAPK1CYP2D6 | |
| SCHEMBL12436705 | 0.94 | POLB (0.57) | POLBL3MBTL1TSHRMAPK1CYP2D6 | |
| SCHEMBL22722039 | 0.94 | POLB (0.57) | POLBL3MBTL1TSHRMAPK1CYP2D6 | |
| SCHEMBL12513426 | 0.94 | POLB (0.57) | POLBL3MBTL1TSHRMAPK1CYP2D6 | |
| SCHEMBL18431056 | 0.90 | MAPT (0.53) | L3MBTL1TSHRMAPK1GAAALDH1A1 | |
| SCHEMBL18431055 | 0.90 | MAPT (0.53) | POLBL3MBTL1TSHRMAPK1GAA | |
| SCHEMBL18947177 | 0.90 | MAPT (0.53) | L3MBTL1TSHRMAPK1GAAALDH1A1 | |
| SCHEMBL18431021 | 0.90 | MAPT (0.53) | L3MBTL1TSHRMAPK1GAAALDH1A1 | |
| SCHEMBL18431102 | 0.88 | GAA (0.54) | POLBL3MBTL1TSHRMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| US-RE48334-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |