SCHEMBL2272202

SCHEMBL2272202

CCCC[Si](CC)(CCCC)NC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2276057 0.95
SCHEMBL15309856 0.94 EPHX1 (0.32) EPHX1TSHRLMNATHRB
SCHEMBL2269940 0.88 TSHR (0.35) EPHX1TSHRLMNATHRB
SCHEMBL2267960 0.83 EPHX1 (0.32) EPHX1TSHRLMNATHRB
SCHEMBL6282145 0.82 TSHR (0.35) TSHRLMNATHRB
SCHEMBL20500214 0.81 TSHR (0.42) EPHX1TSHRLMNATHRB
SCHEMBL2269861 0.77
SCHEMBL20500182 0.76 EPHX1 (0.36) EPHX1TSHRLMNATHRB
SCHEMBL2270615 0.76 TSHR (0.32) TSHRLMNA
SCHEMBL6857972 0.76 TSHR (0.40) EPHX1TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed