SCHEMBL2272238

SCHEMBL2272238

CC[SiH](Cl)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2017630 0.73
SCHEMBL2272072 0.73
SCHEMBL28035288 0.71
SCHEMBL2270676 0.69
SCHEMBL5672762 0.69
SCHEMBL2100763 0.67
SCHEMBL2102464 0.67
SCHEMBL2104283 0.65
SCHEMBL2101115 0.65
SCHEMBL23701149 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5827925-A POLYMERIC MATERIAL BONDED TO DRUG THROUGH PH-SENSITIVE CLEAVABLE COVALENT BOND MONSANTO COMPANY (US) 1998-10-27 US claimed
EP-0540580-B1 POLYMERIC DRUG DELIVERY SYSTEM SEARLE & CO (US) 1994-04-13 EP claimed
EP-0540580-A1 POLYMERIC DRUG DELIVERY SYSTEM. SEARLE & CO (US) 1993-05-12 EP claimed
WO-1992001477-A1 POLYMERIC DRUG DELIVERY SYSTEM G.D. SEARLE & CO. (US) 1992-02-06 WO claimed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-5827925-A POLYMERIC MATERIAL BONDED TO DRUG THROUGH PH-SENSITIVE CLEAVABLE COVALENT BOND MONSANTO COMPANY (US) 1998-10-27 US disclosed
US-5795567-A HYDROFORMYLATION FOLLOWED BY REDUCTIVE AMINATION AND ATTACHING A CHLOROORGANOSILYL COMPOUND; DRUG DELIVERTYSYSTEMS MONSANTO COMPANY (US) 1998-08-18 US disclosed
US-5693319-A HYDROFORMYLATING OLEFINIC-CONTAINING POLYMER IN PRESENCE OF CATALYST, REDUCTIVELY AMINATING MONSANTO COMPANY (US) 1997-12-02 US disclosed
US-5676939-A CROSSLINKING; CONTROLLING DENSITY; DRUG DELIVERY MONSANTO COMPANY (US) 1997-10-14 US disclosed
EP-0540670-B1 METHOD FOR PREPARATION OF CROSSLINKED POLYAMINES MONSANTO CO (US) 1996-03-20 EP disclosed
US-5474767-A Crosslinked; controlled density; water insoluble; residual unsaturation MONSANTO COMPANY (US) 1995-12-12 US disclosed
EP-0540580-B1 POLYMERIC DRUG DELIVERY SYSTEM SEARLE & CO (US) 1994-04-13 EP disclosed
EP-0540580-A1 POLYMERIC DRUG DELIVERY SYSTEM. SEARLE & CO (US) 1993-05-12 EP disclosed
EP-0540670-A1 NOVEL POLYAMINES AND METHOD FOR PREPARATION THEREOF. MONSANTO CO (US) 1993-05-12 EP disclosed
WO-1992001477-A1 POLYMERIC DRUG DELIVERY SYSTEM G.D. SEARLE & CO. (US) 1992-02-06 WO disclosed
WO-1992001730-A1 NOVEL POLYAMINES AND METHOD FOR PREPARATION THEREOF MONSANTO COMPANY (US) 1992-02-06 WO disclosed