Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28521198 | 1.00 | HSD17B10 (0.48) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL22725305 | 1.00 | HSD17B10 (0.48) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL25970105 | 0.95 | HSD17B10 (0.50) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL25970081 | 0.95 | HSD17B10 (0.50) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL25970131 | 0.94 | HSD17B10 (0.49) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL25970274 | 0.91 | HSD17B10 (0.46) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL25983994 | 0.89 | HSD17B10 (0.45) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL25970309 | 0.87 | HSD17B10 (0.45) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL29087405 | 0.84 | HSD17B10 (0.46) | HSD17B10NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL28526303 | 0.82 | HSD17B10 (0.44) | HSD17B10NPC1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874374-B | Hydrogenated pyridopyrimidine derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-113874374-A | Hydrogenated pyridopyrimidine derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-112442029-A | Tetrahydropyrido [3,4-d ] pyrimidine derivative and application thereof in medicine | 四川海思科制药有限公司 | 2021-03-05 | — | — | CN | disclosed |
| WO-2020238791-A1 | HYDROPYRIDOPYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2020-12-03 | — | — | WO | disclosed |