Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23282460 | 1.00 | GAA (0.55) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL22482787 | 0.91 | GAA (0.52) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL8837689 | 0.91 | GAA (0.52) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL22482790 | 0.91 | GAA (0.52) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL29675327 | 0.91 | GAA (0.52) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL8837694 | 0.91 | GAA (0.52) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL8837707 | 0.91 | GAA (0.52) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL22118395 | 0.86 | GAA (0.56) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL24187626 | 0.86 | GAA (0.56) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL24187630 | 0.86 | GAA (0.56) | GAANFKB1NFKB2RELABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220519-A1 | Transaminase mutant and use thereof | ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| EP-3964571-A1 | TRANSAMINASE MUTANT AND APPLICATION THEREOF | Asymchem Life Science (Tianjin) Co., Ltd. (CN) | 2022-03-09 | — | — | EP | disclosed |
| WO-2020237552-A1 | TRANSAMINASE MUTANT AND APPLICATION THEREOF | 凯莱英生命科学技术(天津)有限公司 | 2020-12-03 | — | — | WO | disclosed |