SCHEMBL22729142

SCHEMBL22729142

Cc1cccc(CN2CCCN(CC(=O)O)CCN(CC(=O)O)CCCN(CC(=O)O)CC2)n1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.52
LMNA P02545 2/20 0.52
KMT2A Q03164 5/20 0.48
CHRM2 P08172 2/20 0.48
CHRM1 P11229 2/20 0.48
CHRM3 P20309 2/20 0.48
MAPT P10636 1/20 0.48
MEN1 O00255 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
PKM P14618 1/20 0.45
FAAH O00519 1/20 0.42
CXCR4 P61073 1/20 0.42
EGLN1 Q9GZT9 1/20 0.41
PDE2A O00408 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30023833 1.00 SMN1; SMN2 (0.52) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL21044007 0.96 SMN1; SMN2 (0.49) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL30218419 0.96 SMN1; SMN2 (0.49) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL21044033 0.96 SMN1; SMN2 (0.49) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL30218424 0.96 SMN1; SMN2 (0.49) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL21044127 0.88 SMN1; SMN2 (0.44) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL30218463 0.88 CXCR4 (0.51) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL21044036 0.88 CXCR4 (0.51) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL21044040 0.88 SMN1; SMN2 (0.44) SMN1; SMN2LMNAKMT2ACHRM2CHRM1
SCHEMBL30218443 0.88 SMN1; SMN2 (0.44) SMN1; SMN2LMNAKMT2ACHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113966318-B Compound for chromatographic separation of rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2024-06-18 CN claimed
US-20220259119-A1 COMPOUNDS FOR CHROMATOGRAPHIC SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D-METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I (CZ) 2022-08-18 US claimed
WO-2020244686-A1 COMPOUNDS FOR CHROMATOGRAPHIC SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) 2020-12-10 WO claimed
EP-3747852-A1 COMPOUNDS FOR CHROMATOGRAPHIC SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF Ustav organicke chemie a biochemie AV CR, v.v.i. (CZ) 2020-12-09 EP claimed
US-12215064-B2 Compounds for chromatographic separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2025-02-04 US disclosed
CN-113966318-B Compound for chromatographic separation of rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2024-06-18 CN disclosed
US-20220259119-A1 COMPOUNDS FOR CHROMATOGRAPHIC SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D-METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I (CZ) 2022-08-18 US disclosed
WO-2020244686-A1 COMPOUNDS FOR CHROMATOGRAPHIC SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) 2020-12-10 WO disclosed
EP-3747852-A1 COMPOUNDS FOR CHROMATOGRAPHIC SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF Ustav organicke chemie a biochemie AV CR, v.v.i. (CZ) 2020-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259119-A1 COMPOUNDS FOR CHROMATOGRAPHIC SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D-METALS, METHOD OF SEPARATION, AND USE THEREOF SLC39A3, SCO2, RCOR3 SMN1; SMN2 2225/4885LMNA 681/4885KMT2A 3198/4885
US-12215064-B2 Compounds for chromatographic separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof SLC39A3, SCO2, RCOR3 SMN1; SMN2 2201/4885LMNA 564/4885KMT2A 3187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.