Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 16/20 | 0.90 |
| ▸ | IDH1 | O75874 | 3/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730104 | 1.00 | PRMT5 (0.90) | PRMT5IDH1SMYD3 | |
| SCHEMBL22730106 | 1.00 | PRMT5 (0.90) | PRMT5IDH1SMYD3 | |
| SCHEMBL22449417 | 0.94 | PRMT5 (1.00) | PRMT5IDH1SMYD3 | |
| SCHEMBL19346800 | 0.94 | PRMT5 (1.00) | PRMT5IDH1SMYD3 | |
| SCHEMBL22449416 | 0.94 | PRMT5 (1.00) | PRMT5IDH1SMYD3 | |
| Hydrochloric Acid SCHEMBL19329688 | 0.94 | PRMT5 (0.98) | PRMT5IDH1SMYD3 | |
| Hydrochloric Acid SCHEMBL22449428 | 0.94 | PRMT5 (0.98) | PRMT5IDH1SMYD3 | |
| Hydrochloric Acid SCHEMBL19329687 | 0.94 | PRMT5 (0.98) | PRMT5IDH1SMYD3 | |
| SCHEMBL22449430 | 0.93 | PRMT5 (1.00) | PRMT5IDH1SMYD3 | |
| SCHEMBL22449431 | 0.93 | PRMT5 (1.00) | PRMT5IDH1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426351-B1 | BENZOPIPERIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND HEMOGLOBINOPATHIES | CTXT PTY LTD (AU) | 2020-12-09 | — | — | EP | claimed |