Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730202 | 0.92 | TAAR1 (0.38) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730241 | 0.88 | TAAR1 (0.35) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730179 | 0.88 | TAAR1 (0.35) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730230 | 0.85 | CYP2C19 (0.34) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730162 | 0.84 | TAAR1 (0.40) | TAAR1MAPK1TSHRCYP2C19HIF1A | |
| SCHEMBL8741663 | 0.77 | MAPK1 (0.44) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730200 | 0.75 | MAPK1 (0.42) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730251 | 0.74 | TAAR1 (0.40) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730219 | 0.74 | TAAR1 (0.40) | TAAR1KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL22730246 | 0.74 | TAAR1 (0.36) | TAAR1KCNN4MAPK1ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066427-B2 | Organosilane compounds having bulky substituent and preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| US-20200385411-A1 | ORGANOSILANE COMPOUNDS HAVING BULKY SUBSTITUENT AND PREPARATION THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-12-10 | — | — | US | disclosed |
| EP-3747889-A1 | ORGANOSILANE COMPOUNDS HAVING BULKY SUBSTITUENT AND PREPARATION THEREOF | Shin-Etsu Chemical Co., Ltd. (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066427-B2 | Organosilane compounds having bulky substituent and preparation thereof | C1S, C1R, C9 | TAAR1 1233/4885KCNN4 3367/4885MAPK1 2103/4885 |
| US-20200385411-A1 | ORGANOSILANE COMPOUNDS HAVING BULKY SUBSTITUENT AND PREPARATION THEREOF | C1S, C1R, C9 | TAAR1 1233/4885KCNN4 3367/4885MAPK1 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.