Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730201 | 0.84 | TAAR1 (0.35) | TAAR1CYP2C19CYP3A4MAPK1TSHR | |
| SCHEMBL22730251 | 0.84 | TAAR1 (0.40) | TAAR1CYP2C19CYP3A4MAPK1TSHR | |
| SCHEMBL22730156 | 0.80 | TAAR1 (0.38) | TAAR1CYP2C19CYP3A4MAPK1TSHR | |
| SCHEMBL22730168 | 0.79 | TAAR1 (0.42) | TAAR1SLC6A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22730153 | 0.77 | TAAR1 (0.35) | TAAR1CYP2C19CYP3A4KIF11MAPK1 | |
| SCHEMBL22730162 | 0.77 | TAAR1 (0.40) | TAAR1SLC6A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22730226 | 0.77 | TAAR1 (0.40) | TAAR1SLC6A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22730209 | 0.75 | CYP2C19 (0.34) | TAAR1CYP1A2CYP2C19CYP2D6KIF11 | |
| SCHEMBL6889501 | 0.74 | SLC6A2 (0.52) | TAAR1SLC6A2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22730237 | 0.72 | TAAR1 (0.42) | TAAR1SLC6A2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066427-B2 | Organosilane compounds having bulky substituent and preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| US-20200385411-A1 | ORGANOSILANE COMPOUNDS HAVING BULKY SUBSTITUENT AND PREPARATION THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-12-10 | — | — | US | disclosed |
| EP-3747889-A1 | ORGANOSILANE COMPOUNDS HAVING BULKY SUBSTITUENT AND PREPARATION THEREOF | Shin-Etsu Chemical Co., Ltd. (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066427-B2 | Organosilane compounds having bulky substituent and preparation thereof | C1S, C1R, C9 | TAAR1 1233/4885SLC6A2 4250/4885CYP1A2 93/4885 |
| US-20200385411-A1 | ORGANOSILANE COMPOUNDS HAVING BULKY SUBSTITUENT AND PREPARATION THEREOF | C1S, C1R, C9 | TAAR1 1233/4885SLC6A2 4250/4885CYP1A2 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.