⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705269 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28924805 | 0.97 | — | — | |
| SCHEMBL14876899 | 0.79 | TSHR (0.36) | — | |
| SCHEMBL9107998 | 0.78 | GRM7 (0.41) | — | |
| SCHEMBL9442158 | 0.78 | KDM5B (0.36) | — | |
| SCHEMBL1757441 | 0.77 | — | — | |
| SCHEMBL1757440 | 0.74 | — | — | |
| SCHEMBL12989501 | 0.74 | KMT2A (0.33) | — | |
| SCHEMBL8212375 | 0.74 | — | — | |
| SCHEMBL149473 | 0.74 | CYP2D6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466849-B | N-substituted-3, 4- (fused 5-ring) -5-phenyl-pyrrolidin-2-one compounds as ISOQC and/or inhibitors of QC enzymes | 欣尼克免疫有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20230338571-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230257393-A1 | MACROMOLECULE-SUPPORTED THIENOAZEPINE COMPOUNDS, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-08-17 | — | — | US | disclosed |
| US-11654199-B2 | Thienoazepine immunoconjugates, and uses thereof | BOLT BIOTHERAPEUTICS, INC. (US) | 2023-05-23 | — | — | US | disclosed |
| CN-114466849-A | N-substituted-3, 4- (fused 5-ring) -5-phenyl-pyrrolidin-2-one compounds as inhibitors of ISOQC and/or QC enzymes | 欣尼克免疫有限公司 | 2022-05-10 | — | — | CN | disclosed |
| US-20210396629-A1 | DEVICE FOR COLLECTING VOLATILE ORGANIC COMPOUNDS | L'ETAT FRANÇAIS REPRÉSENTÉ PAR LE MINISTÈRE DE L'INTÉRIEUR (FR) | 2021-12-23 | — | — | US | disclosed |
| EP-3881048-A1 | DEVICE FOR REMOVING VOLATILE ORGANIC COMPOUNDS | L'etat Français Représenté Par Le Ministère De L'intérieur (FR) | 2021-09-22 | — | — | EP | disclosed |
| US-20210128744-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-05-06 | — | — | US | disclosed |
| WO-2021081407-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| WO-2021081402-A1 | MACROMOLECULE-SUPPORTED THIENOAZEPINE COMPOUNDS, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| EP-1713798-A4 | C10 CYCLOPENTYL ESTER SUBSTITUTED TAXANES | UNIV FLORIDA STATE RES FOUND (US) | 2007-12-05 | — | — | EP | disclosed |
| EP-1713798-A4 | C10 CYCLOPENTYL ESTER SUBSTITUTED TAXANES | UNIV FLORIDA STATE RES FOUND (US) | 2007-12-05 | — | — | EP | disclosed |
| CN-1918152-A | C10 cyclopentyl ester substituted taxanes | UNIV FLORIDA STATE RES FOUND (US) | 2007-02-21 | — | — | CN | disclosed |
| EP-1713798-A2 | C10 CYCLOPENTYL ESTER SUBSTITUTED TAXANES | Florida State University Research Foundation, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1713798-A2 | C10 CYCLOPENTYL ESTER SUBSTITUTED TAXANES | Florida State University Research Foundation, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005079319-A3 | C10 CYCLOPENTYL ESTER SUBSTITUTED TAXANES | UNIV FLORIDA STATE RES FOUND (US) | 2005-11-17 | — | — | WO | disclosed |
| US-20050228037-A1 | C10 cyclopentyl ester substituted taxanes | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-10-13 | — | — | US | disclosed |
| US-20050228037-A1 | C10 cyclopentyl ester substituted taxanes | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-10-13 | — | — | US | disclosed |
| WO-2005079319-A2 | C10 CYCLOPENTYL ESTER SUBSTITUTED TAXANES | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005079319-A2 | C10 CYCLOPENTYL ESTER SUBSTITUTED TAXANES | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2005-09-01 | — | — | WO | disclosed |