Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31037032 | 1.00 | HIF1A (0.51) | HIF1ACASRPTGS2F10TP53 | |
| SCHEMBL22733090 | 0.86 | IDO1 (0.47) | HIF1APTGS2PTGS1CYP1A2NPC1 | |
| SCHEMBL31037046 | 0.86 | IDO1 (0.47) | HIF1APTGS2PTGS1CYP1A2NPC1 | |
| SCHEMBL31037045 | 0.86 | HIF1A (0.54) | HIF1ATP53CYP1A2NPC1RAB9A | |
| SCHEMBL25975633 | 0.86 | HIF1A (0.54) | HIF1ATP53CYP1A2NPC1RAB9A | |
| SCHEMBL25975640 | 0.85 | HIF1A (0.49) | HIF1ATP53CYP1A2NPC1RAB9A | |
| SCHEMBL22733091 | 0.76 | NPC1 (0.43) | HIF1ANPC1RAB9APAX8NPBWR1 | |
| SCHEMBL22733280 | 0.76 | HIF1A (0.61) | HIF1APTGS2TP53PTGS1CYP1A2 | |
| SCHEMBL31037072 | 0.76 | HIF1A (0.61) | HIF1APTGS2TP53PTGS1CYP1A2 | |
| SCHEMBL22733034 | 0.74 | NPC1 (0.43) | HIF1ATP53CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454068-A | Benzoindazolone compounds and intermediates thereof | LMITO药业株式会社 | 2021-09-28 | — | — | CN | claimed |
| US-20230255904-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING NAPHTHOQUINONE-BASED COMPOUND AND IMMUNE CHECKPOINT INHIBITOR AS ACTIVE INGREDIENTS | NADIANBIO LTD. (KR) | 2023-08-17 | — | — | US | disclosed |
| CN-113454068-A | Benzoindazolone compounds and intermediates thereof | LMITO药业株式会社 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020246807-A2 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, CONTAINING NAPHTHOQUINONE COMPOUND | 주식회사 엘마이토테라퓨틱스 | 2020-12-10 | — | — | WO | disclosed |
| WO-2020242277-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING NAPHTHOQUINONE DERIVATIVE | 주식회사 엘마이토테라퓨틱스 | 2020-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255904-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING NAPHTHOQUINONE-BASED COMPOUND AND IMMUNE CHECKPOINT INHIBITOR AS ACTIVE INGREDIENTS | PDCD1, CD274, PDCD10 | HIF1A 3197/4885CASR 4738/4885PTGS2 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.