SCHEMBL227342

SCHEMBL227342

CCC(O)C(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
CETP P11597 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7312976 0.75
SCHEMBL765946 0.75
SCHEMBL469203 0.75
SCHEMBL25427133 0.75 TSHR (0.53) TSHRCETP
SCHEMBL12972030 0.74 TSHR (0.52) TSHRCETP
SCHEMBL20342302 0.74 TSHR (0.52) TSHRCETP
SCHEMBL14850907 0.73
SCHEMBL899353 0.73
SCHEMBL22072954 0.73
Hydrochloric Acid SCHEMBL7065801 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101351429-B Process for the preparation and purification of hydrofluoroolefins DU PONT 2014-03-05 CN disclosed
US-8399723-B2 Processes for production and purification of hydrofluoroolefins E I DU PONT DE NEMOURS AND COMPANY (US) 2013-03-19 US disclosed
US-20120004475-A1 PROCESSES FOR PRODUCTION AND PURIFICATION OF HYDROFLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-05 US disclosed
US-20110118512-A1 PROCESSES FOR PRODUCTION AND PURIFICATION OF HYDROFLUOROOLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-19 US disclosed
US-7897823-B2 Process for production of azeotrope compositions comprising hydrofluoroolefin and hydrogen fluoride and uses of said azeotrope compositions in separation processes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-01 US disclosed
US-20060106263-A1 Processes for production and purification of hydrofluoroolefins THE CHEMOURS COMPANY FC, LLC 2006-05-18 US disclosed