Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 7/20 | 0.72 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22734410 | 1.00 | F2RL1 (0.72) | F2RL1ACACBACACAALDH1A1MAPK1 | |
| SCHEMBL16598496 | 0.94 | F2RL1 (0.74) | F2RL1ACACBACACAALDH1A1 | |
| SCHEMBL16614674 | 0.94 | F2RL1 (0.74) | F2RL1ACACBACACAALDH1A1 | |
| SCHEMBL16614677 | 0.94 | F2RL1 (0.74) | F2RL1ACACBACACAALDH1A1 | |
| SCHEMBL16615123 | 0.91 | F2RL1 (0.72) | F2RL1ACACBACACAALDH1A1MAPK1 | |
| SCHEMBL16615166 | 0.91 | F2RL1 (0.72) | F2RL1ACACBACACAALDH1A1MAPK1 | |
| SCHEMBL16598690 | 0.90 | F2RL1 (0.71) | F2RL1ACACBACACAALDH1A1MAPK1 | |
| SCHEMBL18169482 | 0.90 | F2RL1 (0.71) | F2RL1ACACBACACAALDH1A1MAPK1 | |
| SCHEMBL16614886 | 0.90 | F2RL1 (0.71) | F2RL1ACACBACACAALDH1A1MAPK1 | |
| SCHEMBL16614726 | 0.90 | F2RL1 (0.75) | F2RL1ACACBACACAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200383985-A1 | Inhibitors of Protease Activated Receptor-2 | MONASH UNIVERSITY (AU) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200383985-A1 | Inhibitors of Protease Activated Receptor-2 | F2RL1, F2R, F2RL3 | F2RL1 1/4885ACACB 3131/4885ACACA 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.