Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.96 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.96 |
| ▸ | MEN1 | O00255 | 7/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.96 |
| ▸ | TP53 | P04637 | 6/20 | 0.96 |
| ▸ | HTT | P42858 | 5/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.96 |
| ▸ | USP2 | O75604 | 3/20 | 0.96 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MPI | P34949 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Broxyquinoline SCHEMBL27633003 | 1.00 | KDM4E (0.96) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL27551522 | 0.98 | KDM4E (0.93) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL115293 | 0.98 | KDM4E (1.00) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL30485535 | 0.98 | KDM4E (1.00) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL29607319 | 0.98 | KDM4E (1.00) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL28909008 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL261708 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL28500050 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL28528459 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1MEN1KMT2ATP53 | |
| Broxyquinoline SCHEMBL31157810 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200388791-A1 | ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING CAPPING LAYER AND USE | VALIANT CO., LTD. | 2020-12-10 | — | — | US | disclosed |