Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 13/20 | 0.36 |
| ▸ | GCG | P01275 | 6/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480743 | 1.00 | RIPK2 (0.36) | RIPK2GCGGCGR | |
| SCHEMBL29480665 | 0.90 | RIPK2 (0.33) | RIPK2GCGGCGR | |
| SCHEMBL29480711 | 0.89 | RIPK2 (0.35) | RIPK2GCG | |
| SCHEMBL29480497 | 0.86 | RIPK2 (0.34) | RIPK2GCG | |
| SCHEMBL22736254 | 0.86 | RIPK2 (0.34) | RIPK2GCG | |
| SCHEMBL22736340 | 0.85 | RIPK2 (0.36) | RIPK2GCG | |
| SCHEMBL29480728 | 0.85 | RIPK2 (0.36) | RIPK2GCG | |
| SCHEMBL29480676 | 0.81 | GCG (0.32) | GCGGCGR | |
| SCHEMBL22716927 | 0.79 | RIPK2 (0.33) | RIPK2GCG | |
| SCHEMBL29480738 | 0.79 | RIPK2 (0.33) | RIPK2GCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |