Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 2/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480753 | 1.00 | GCG (0.30) | GCGGCGRGRM4 | |
| SCHEMBL22736041 | 0.91 | GRM4 (0.32) | GCGGCGRGRM4 | |
| SCHEMBL29567639 | 0.91 | GRM4 (0.32) | GCGGCGRGRM4 | |
| SCHEMBL29480678 | 0.89 | — | — | |
| SCHEMBL29480676 | 0.86 | GCG (0.32) | GCGGCGRGRM4 | |
| SCHEMBL22736539 | 0.84 | JAK2 (0.31) | GCG | |
| SCHEMBL29480732 | 0.84 | JAK2 (0.31) | GCG | |
| SCHEMBL22735964 | 0.81 | GRM4 (0.32) | GRM4 | |
| SCHEMBL22735968 | 0.80 | — | — | |
| SCHEMBL29480751 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020240586-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2020-12-03 | — | — | WO | disclosed |