Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1240087 | 0.85 | TSHR (0.48) | TSHRCHRM2MAPTABCC4ALDH1A1 | |
| SCHEMBL1242584 | 0.82 | TSHR (0.48) | TSHRCHRM2MAPTABCC4ALDH1A1 | |
| SCHEMBL7354444 | 0.82 | LSS (0.38) | TSHRFAAHTRPV1HIF1A | |
| SCHEMBL7522844 | 0.80 | HIF1A (0.53) | TSHRFAAHTRPV1MAPTABCC4 | |
| SCHEMBL455320 | 0.80 | HIF1A (0.53) | TSHRFAAHTRPV1MAPTABCC4 | |
| SCHEMBL24287754 | 0.80 | HIF1A (0.53) | TSHRFAAHTRPV1MAPTABCC4 | |
| SCHEMBL1701705 | 0.80 | HIF1A (0.53) | TSHRFAAHTRPV1MAPTABCC4 | |
| SCHEMBL9246360 | 0.80 | HIF1A (0.53) | TSHRFAAHTRPV1MAPTABCC4 | |
| SCHEMBL107549 | 0.80 | HIF1A (0.53) | TSHRFAAHTRPV1MAPTABCC4 | |
| SCHEMBL5336674 | 0.80 | HIF1A (0.53) | TSHRFAAHTRPV1MAPTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243540-A1 | MACROCYCLIC LIPIDS | TRANSLATE BIO, INC. (US) | 2020-12-03 | — | — | WO | disclosed |