Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.42 |
| ▸ | CBLB | Q13191 | 17/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947538 | 0.76 | MAP3K5 (0.48) | MAP3K5CBLB | |
| SCHEMBL945176 | 0.72 | MAP3K5 (0.76) | MAP3K5 | |
| SCHEMBL14482006 | 0.70 | MAP3K5 (0.41) | MAP3K5CBLB | |
| SCHEMBL14681926 | 0.68 | MAP3K5 (0.54) | MAP3K5CBLB | |
| SCHEMBL12946065 | 0.67 | MAP3K5 (0.77) | MAP3K5 | |
| SCHEMBL22739302 | 0.66 | MAP3K5 (0.56) | MAP3K5CBLB | |
| SCHEMBL23720984 | 0.66 | IRAK4 (0.47) | MAP3K5CBLB | |
| SCHEMBL12943417 | 0.66 | MAP3K5 (0.52) | MAP3K5CBLB | |
| SCHEMBL945007 | 0.66 | MAP3K5 (0.52) | MAP3K5CBLB | |
| SCHEMBL15408426 | 0.65 | RIPK2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363797-B1 | ORAL DOSAGE FORM OF APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2020-12-02 | — | — | EP | disclosed |