Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 16/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272428 | 1.00 | CHRM1 (0.75) | CHRM1 | |
| SCHEMBL12802594 | 0.94 | CHRM1 (0.75) | CHRM1 | |
| SCHEMBL12959050 | 0.90 | CHRM1 (0.62) | CHRM1 | |
| SCHEMBL6888427 | 0.89 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL12802929 | 0.89 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL6889896 | 0.88 | CHRM1 (0.78) | CHRM1 | |
| SCHEMBL23672626 | 0.88 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL17656776 | 0.87 | CHRM1 (0.65) | CHRM1 | |
| SCHEMBL16937080 | 0.86 | CHRM1 (1.00) | CHRM1 | |
| SCHEMBL2226588 | 0.85 | CHRM1 (0.74) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512243-A1 | QUINOLINE AMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | Merck Sharp & Dohme Corp. (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084368-A1 | QUINOLINE AMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |