Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782872 | 1.00 | MAPK1 (0.31) | MAPK1BRD4BRD2 | |
| SCHEMBL24451121 | 0.87 | BRD4 (0.37) | BRD4BRD2 | |
| SCHEMBL13036914 | 0.85 | BRD4 (0.35) | BRD4BRD2 | |
| SCHEMBL24629464 | 0.83 | — | — | |
| SCHEMBL28251386 | 0.80 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL18061559 | 0.76 | CRBN (0.32) | BRD4 | |
| SCHEMBL15199073 | 0.76 | MEN1 (0.35) | — | |
| SCHEMBL9962273 | 0.76 | POLB (0.32) | — | |
| SCHEMBL17517145 | 0.72 | PIK3CD (0.35) | — | |
| SCHEMBL22472646 | 0.72 | DPP4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239999-A1 | SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-03 | — | — | WO | disclosed |