Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 4/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 15/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23870034 | 1.00 | MAP3K14 (0.37) | MAP3K14MAP4K4GRM5 | |
| SCHEMBL22744222 | 0.95 | MAP3K14 (0.38) | MAP3K14MAP4K4 | |
| SCHEMBL23869944 | 0.84 | MAP4K4 (0.36) | MAP3K14MAP4K4 | |
| SCHEMBL23870160 | 0.83 | MAP4K4 (0.36) | MAP3K14MAP4K4 | |
| SCHEMBL22744587 | 0.83 | MAP4K4 (0.39) | MAP3K14MAP4K4 | |
| SCHEMBL22744191 | 0.83 | MAP4K4 (0.37) | MAP3K14MAP4K4 | |
| SCHEMBL22744220 | 0.81 | MAP4K4 (0.36) | MAP3K14MAP4K4 | |
| SCHEMBL22744260 | 0.81 | MAP4K4 (0.36) | MAP3K14MAP4K4 | |
| SCHEMBL22744256 | 0.81 | MAP4K4 (0.36) | MAP3K14MAP4K4 | |
| SCHEMBL22715910 | 0.78 | MAP3K14 (0.59) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239999-A1 | SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-03 | — | — | WO | disclosed |