Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 19/20 | 0.45 |
| ▸ | PKD1 | P98161 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471436 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL31026170 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL29439438 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL22715474 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL22716310 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL22715612 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL22715476 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL22715022 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL22715021 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 | |
| SCHEMBL29439425 | 1.00 | MAP3K14 (0.45) | MAP3K14PKD1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239999-A1 | SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-03 | — | — | WO | disclosed |