Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9610945 | 0.84 | NR2E1 (0.66) | NR2E1 | |
| SCHEMBL12361914 | 0.80 | NR2E1 (0.64) | NR2E1 | |
| SCHEMBL31718472 | 0.80 | NR2E1 (0.61) | NR2E1 | |
| SCHEMBL10104281 | 0.78 | NR2E1 (0.73) | NR2E1 | |
| SCHEMBL9609575 | 0.76 | NR2E1 (0.71) | NR2E1 | |
| SCHEMBL15189550 | 0.76 | NR2E1 (0.70) | NR2E1 | |
| SCHEMBL4454872 | 0.75 | NR2E1 (0.69) | NR2E1 | |
| SCHEMBL1505804 | 0.75 | NR2E1 (0.69) | NR2E1 | |
| SCHEMBL12354435 | 0.75 | NR2E1 (0.69) | NR2E1 | |
| SCHEMBL21950471 | 0.75 | NR2E1 (0.69) | NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053220-B2 | Process for 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline | LAURUS LABS LTD (IN) | 2021-07-06 | — | — | US | disclosed |
| US-20200377475-A1 | AN IMPROVED PROCESS FOR 3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL) ANILINE | LAURUS LABS LTD (IN) | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053220-B2 | Process for 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline | CYP4F3, AZI2, CYP1A2 | NR2E1 2946/4885 |
| US-20200377475-A1 | AN IMPROVED PROCESS FOR 3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL) ANILINE | CYP4F3, CYP1A2, CYP4B1 | NR2E1 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.