Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22718576 | 0.90 | TRPV1 (0.52) | TRPV1HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL22718799 | 0.89 | TRPV1 (0.54) | TRPV1HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL22718795 | 0.89 | TRPV1 (0.54) | TRPV1HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL22718546 | 0.84 | HDAC1 (0.48) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL22718542 | 0.84 | HDAC1 (0.48) | HDAC1HDAC3HDAC8HDAC6HDAC2 | |
| SCHEMBL29427191 | 0.84 | TRPV1 (0.48) | TRPV1ESR1MAPTXBP1NPSR1 | |
| SCHEMBL22718709 | 0.81 | HDAC6 (0.55) | TRPV1HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL22718705 | 0.81 | HDAC6 (0.55) | TRPV1HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL29427185 | 0.81 | HDAC6 (0.55) | TRPV1HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL22718537 | 0.79 | TRPV1 (0.55) | TRPV1HDAC1HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-07-07 | — | — | US | disclosed |
| WO-2020242719-A2 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2020-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213052-A1 | INHIBITORS OF RNA-BINDING PROTEINS, COMPOSITIONS THEREOF, AND THERAPEUTIC USES THEROF | HNRNPF, RBM3, RBM15 | TRPV1 4640/4885HDAC1 1875/4885HDAC3 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.