Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 5/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19919699 | 0.81 | KDM4E (0.42) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL22747308 | 0.80 | NOTUM (0.41) | KMT2AMEN1 | |
| SCHEMBL30345167 | 0.79 | KDM4E (0.43) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL22977378 | 0.79 | KDM4E (0.43) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL3632915 | 0.74 | KDM4E (0.50) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL31214189 | 0.74 | KDM4E (0.60) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL31661354 | 0.74 | KDM4E (0.38) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL10857110 | 0.72 | KDM4E (0.48) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL8481059 | 0.72 | KDM4E (0.48) | KDM4ETSHRALOX15ACMSDTDP1 | |
| SCHEMBL27882830 | 0.72 | KDM4E (0.48) | KDM4ETSHRALOX15ACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243135-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-12-03 | — | — | WO | disclosed |