SCHEMBL22747653

SCHEMBL22747653

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5c6c(ccc54)C4(c5ccccc5-c5ccccc54)c4ccccc4-6)c3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25121762 0.98 PDE10A (0.32) KDM4EATML3MBTL1RXFP1PDE10A
SCHEMBL25966409 0.96 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL25966412 0.96 KDM4E (0.35) KDM4EATML3MBTL1RXFP1
SCHEMBL25121595 0.96 PDE10A (0.34) KDM4EATML3MBTL1RXFP1PDE10A
SCHEMBL25966511 0.95 KDM4E (0.34) KDM4EATML3MBTL1RXFP1PDE10A
SCHEMBL25966509 0.94 KDM4E (0.31) KDM4EATML3MBTL1PDE10A
SCHEMBL18505588 0.94 KDM4E (0.31) KDM4EATML3MBTL1PDE10A
SCHEMBL25121846 0.94 KDM4E (0.33) KDM4EATML3MBTL1RXFP1PDE10A
SCHEMBL25121864 0.93 MEN1 (0.33) KDM4EATML3MBTL1
SCHEMBL23604094 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230108986-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-06 US disclosed
US-11424418-B2 Metal complex organic electroluminescent material and organic electroluminescent device SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2022-08-23 US disclosed
US-20210198567-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-07-01 US disclosed
US-20200381633-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-12-03 US disclosed