Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CPT2 | P23786 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748621 | 1.00 | FFAR1 (0.50) | FFAR1CPT2TDP1MEN1KMT2A | |
| SCHEMBL1114707 | 1.00 | FFAR1 (0.50) | FFAR1CPT2TDP1MEN1KMT2A | |
| SCHEMBL27403262 | 0.92 | FFAR1 (0.43) | FFAR1CPT2TDP1MEN1KMT2A | |
| SCHEMBL14925256 | 0.85 | FFAR1 (0.73) | FFAR1CPT2TDP1MEN1KMT2A | |
| SCHEMBL20711057 | 0.85 | MEN1 (0.50) | MEN1KMT2AHPGDRECQLHSD17B10 | |
| SCHEMBL20457437 | 0.85 | MEN1 (0.50) | MEN1KMT2AHPGDRECQLHSD17B10 | |
| SCHEMBL14627982 | 0.85 | MEN1 (0.50) | MEN1KMT2AHPGDRECQLHSD17B10 | |
| SCHEMBL6988854 | 0.84 | TSHR (0.40) | FFAR1CPT2TDP1MEN1KMT2A | |
| SCHEMBL21015892 | 0.83 | TSHR (0.50) | LMNACA12CA14CA2CA7 | |
| SCHEMBL10259053 | 0.83 | FFAR1 (0.48) | FFAR1CPT2TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245291-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |