Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748814 | 0.84 | CNR1 (0.47) | CDC25ACYP1A2CYP2C19GAAMEN1 | |
| SCHEMBL8519956 | 0.83 | NOTUM (0.54) | RARBCDC25ACYP1A2CYP2C19GAA | |
| SCHEMBL2804808 | 0.76 | NOTUM (0.41) | MEN1KMT2AKAT8PPARACNR2 | |
| SCHEMBL11638318 | 0.74 | CNR2 (0.52) | CDC25ACYP1A2CYP2C19GAAMEN1 | |
| SCHEMBL10461123 | 0.72 | CNR2 (0.53) | CDC25ACYP1A2CYP2C19GAAMEN1 | |
| SCHEMBL28178378 | 0.72 | CNR2 (0.56) | CDC25ACNR2CNR1 | |
| SCHEMBL9807558 | 0.71 | CDC25A (0.40) | CDC25AMEN1KMT2ACNR2 | |
| SCHEMBL2451895 | 0.71 | CDC25A (0.46) | CDC25AMEN1KMT2ACNR2CNR1 | |
| SCHEMBL22748607 | 0.70 | RARB (0.43) | RARBRARARARGCYP1A2CYP2C19 | |
| SCHEMBL22748719 | 0.70 | RARB (0.43) | RARBRARARARGCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245291-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | claimed |
| WO-2020245291-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |