Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22748237 | 1.00 | GRM1 (0.36) | GRM1NAAAALDH1A1LMNAPOLB | |
| SCHEMBL22748764 | 0.99 | MTOR (0.36) | GRM1NAAAALDH1A1LMNAPOLB | |
| SCHEMBL22748456 | 0.99 | MTOR (0.36) | GRM1NAAAALDH1A1LMNAPOLB | |
| SCHEMBL22748457 | 0.99 | MTOR (0.36) | GRM1NAAAALDH1A1LMNAPOLB | |
| SCHEMBL23234046 | 0.88 | GRM1 (0.43) | GRM1ALDH1A1LMNAPOLBMTOR | |
| SCHEMBL22748735 | 0.86 | MAPT (0.37) | NAAAALDH1A1LMNAPOLBMAPT | |
| SCHEMBL22748928 | 0.86 | MAPT (0.37) | NAAAALDH1A1LMNAPOLBMAPT | |
| SCHEMBL22748853 | 0.86 | MAPT (0.37) | NAAAALDH1A1LMNAPOLBMAPT | |
| SCHEMBL22748299 | 0.85 | TP53 (0.37) | NAAAPOLBMAPTHTTMEN1 | |
| SCHEMBL22748435 | 0.85 | TP53 (0.37) | NAAAPOLBMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |