Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10260946 | 0.86 | HDAC6 (0.40) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL19699862 | 0.80 | CHRM2 (0.39) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL3708301 | 0.79 | HDAC6 (0.34) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL3293559 | 0.79 | HDAC6 (0.40) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL20762898 | 0.79 | GBA1 (0.39) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL19607386 | 0.79 | CA14 (0.39) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL9354313 | 0.78 | GBA1 (0.34) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL24980372 | 0.77 | GBA1 (0.36) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL17337834 | 0.77 | GBA1 (0.36) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL19945257 | 0.77 | GBA1 (0.36) | GBA1HDAC6CA14HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980057-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | Institut Curie (FR) | 2022-04-13 | — | — | EP | disclosed |
| WO-2020245321-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2020-12-10 | — | — | WO | disclosed |