SCHEMBL2274886

SCHEMBL2274886

NSn1ccnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19662697 0.72
SCHEMBL1727812 0.72
SCHEMBL1727810 0.72
SCHEMBL27678809 0.67
SCHEMBL31316927 0.64
SCHEMBL16588890 0.64
SCHEMBL5049805 0.62
SCHEMBL917244 0.62 CYP19A1 (0.41)
SCHEMBL3429163 0.61 FOLH1 (0.33)
SCHEMBL60018 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119592953-A Etching liquid composition 东进世美肯株式会社 2025-03-11 CN claimed
CN-112385019-A Etchant composition 朗姆研究公司 2021-02-19 CN claimed
CN-119592953-A Etching liquid composition 东进世美肯株式会社 2025-03-11 CN disclosed
US-11345852-B2 Etchant composition LAM RESEARCH CORPORATION (US) 2022-05-31 US disclosed
US-20210277308-A1 ETCHANT COMPOSITION LAM RESEARCH AG (AT) 2021-09-09 US disclosed
CN-112385019-A Etchant composition 朗姆研究公司 2021-02-19 CN disclosed
US-8003643-B2 Inhibitors of Akt activity MERCK SHARP & DOHME CORP. (US) 2011-08-23 US disclosed
US-20100075970-A1 INHIBITORS OF AKT ACTIVITY MERCK SHARP & DOHME CORP. 2010-03-25 US disclosed
US-7655649-B2 Cancer; N,N-dimethyl-5-phenyl-6-(4-{[4-(5-pyridin-2-yl-1H-pyrazol-3-yl)piperidin-1-yl]methyl}phenyl) pyridazin-3-amine;; serine/threonine kinase (Akt) suppression; increased cellular potency or solubility, enhanced pharmacokinetic properties MERCK SHARP & DOHME CORP. (US) 2010-02-02 US disclosed
EP-1737843-A4 INHIBITORS OF AKT ACTIVITY MERCK & CO INC (US) 2009-01-28 EP disclosed
US-20080280889-A1 Inhibitors of Akt Activity MERCK SHARP & DOHME CORP. 2008-11-13 US disclosed
EP-1737843-A1 INHIBITORS OF AKT ACTIVITY Merck & Co., Inc. (US) 2007-01-03 EP disclosed
WO-2005100344-A1 INHIBITORS OF AKT ACTIVITY MERCK & CO., INC. (US) 2005-10-27 WO disclosed