Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416609 | 0.86 | PARP1 (0.49) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL857761 | 0.86 | PARP1 (0.49) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL22749457 | 0.77 | POLB (0.34) | PARP1ALDH1A1MAPT | |
| SCHEMBL19890011 | 0.77 | AAK1 (0.40) | EGFRPARP1DYRK1AMAPTCYP1A2 | |
| SCHEMBL25630850 | 0.76 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL856083 | 0.73 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DENPP1 | |
| SCHEMBL856547 | 0.73 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL29461277 | 0.73 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL686704 | 0.72 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DEGFR | |
| SCHEMBL29416410 | 0.72 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020246488-A1 | COMPOUND STABILIZING COMPLEX CONTAINING NuMA1 AND CKAP5 | 第一三共株式会社 | 2020-12-10 | — | — | WO | disclosed |
| WO-2020246487-A1 | COMPOUNDS HAVING DISPIRO DIKETOPIPERAZINE STRUCTURE | 第一三共株式会社 | 2020-12-10 | — | — | WO | disclosed |