⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593411 | 0.76 | — | — | |
| SCHEMBL2762589 | 0.75 | — | — | |
| SCHEMBL17629681 | 0.74 | — | — | |
| SCHEMBL18131671 | 0.72 | — | — | |
| SCHEMBL14562497 | 0.72 | — | — | |
| SCHEMBL28317814 | 0.70 | — | — | |
| SCHEMBL3426075 | 0.68 | — | — | |
| SCHEMBL3660058 | 0.67 | — | — | |
| SCHEMBL3748544 | 0.67 | — | — | |
| SCHEMBL17925957 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980422-A1 | IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER | Mirati Therapeutics, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |
| WO-2020247475-A1 | IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER | Mirati Therapeutics, Inc. (US) | 2020-12-10 | — | — | WO | disclosed |