Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 18/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930114 | 0.80 | ALK (0.46) | PTK2CDK7CDK9 | |
| SCHEMBL19929908 | 0.79 | ALK (0.36) | PTK2 | |
| SCHEMBL19921229 | 0.78 | PTK2 (0.76) | PTK2 | |
| SCHEMBL19929854 | 0.78 | ALK (0.37) | PTK2 | |
| SCHEMBL19929858 | 0.77 | KDM4E (0.48) | PTK2 | |
| SCHEMBL19930112 | 0.75 | ALK (0.38) | PTK2 | |
| SCHEMBL19929896 | 0.75 | PTK2 (0.42) | PTK2CDK7CDK9MAP4K1 | |
| SCHEMBL19929855 | 0.75 | ALK (0.38) | PTK2 | |
| SCHEMBL19669895 | 0.72 | CDK7 (0.66) | PTK2CDK7CDK9MAP4K1 | |
| SCHEMBL31229775 | 0.72 | PTK2 (0.43) | PTK2CDK7CDK9MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290420-B1 | PYRIMIDINE PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF | UNIV XIAMEN (CN) | 2020-12-09 | — | — | EP | disclosed |