Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29968444 | 0.98 | TSHR (0.37) | TSHRL3MBTL3L3MBTL1 | |
| SCHEMBL21841000 | 0.87 | KDM1A (0.35) | TSHR | |
| SCHEMBL18766281 | 0.86 | CYP2D6 (0.35) | TSHR | |
| SCHEMBL22724562 | 0.86 | TSHR (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL29968181 | 0.85 | KDM1A (0.34) | TSHR | |
| SCHEMBL19872316 | 0.81 | OPRL1 (0.30) | — | |
| SCHEMBL19692857 | 0.78 | KDM1A (0.30) | — | |
| SCHEMBL27480808 | 0.78 | TSHR (0.37) | TSHRL3MBTL3L3MBTL1 | |
| SCHEMBL18642963 | 0.78 | TSHR (0.37) | TSHRL3MBTL3L3MBTL1 | |
| SCHEMBL343237 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2023109909-A1 | AROMATIC HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND USES THEREOF | 上海翊石医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |
| EP-3464272-B1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2021-12-08 | — | — | EP | disclosed |
| EP-3312164-B1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES LLC (US) | 2020-12-09 | — | — | EP | disclosed |