Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22384126 | 0.98 | KLKB1 (0.40) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16295925 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305864 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16342990 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305545 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305935 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16306133 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305547 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16306132 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16295922 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4ITGB3ITGA2BKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008056-B1 | NOVEL GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-12-09 | — | — | EP | disclosed |